What is the difference between aldol addition and aldol condensation

Schmidt, who independently published on this topic in and An example is the synthesis of dibenzylideneacetone. Quantitative yields in Claisen-Schmidt reactions have been reported in the absence of solvent using sodium hydroxide as the base and plus benzaldehydes.

The first part of this reaction is an aldol reaction, the second part a dehydration—an elimination reaction Involves removal of a water molecule or an alcohol molecule. Dehydration may be accompanied by decarboxylation when an activated carboxyl group is present.

The aldol addition product can be dehydrated via two mechanisms; a strong base like potassium t -butoxide, potassium hydroxide or sodium hydride in an enolate mechanism, or in an acid-catalyzed enol mechanism. Depending on the nature of the desired product, the aldol condensation may be carried out under two broad types of conditions: kinetic control or thermodynamic control. What is Aldol Condensation 3. What is Claisen Condensation 4. According to its mechanism, we can categorize an aldol reaction aldol condensation is also named as aldol reaction as a coupling reaction.

This aldol reaction is followed by a dehydration reaction, which gives a conjugated enone. Moreover, there are two steps in an aldol condensation reaction.

These are the aldol reaction and dehydration reaction. However, we can sometimes observe that there is a dicarboxylic reaction, as well.

Usually, dehydration of the aldol product can occur in two ways: in a strong base-catalyzed mechanism or in an acid-catalyzed mechanism. Aldol condensation process is very important in organic synthesis because this reaction is a precise way to form a carbon-carbon bond. Claisen condensation is a type of coupling reaction in which a carbon-carbon bond is formed between two esters or one ester and a carbonyl compound.

Furthermore, this reaction has two major steps: aldol reaction and condensation reaction. In the aldol reaction, an enol or an enolate ion reacts with a carbonyl compound to give a beta-hydroxyaldehyde or beta-hydroxyketone. Moreover, in the next step, dehydration occurs, giving a conjugated enone. The reaction is as follows:. Figure Aldol Condensation Reaction. The aldol condensation reaction is very important in organic synthesis reactions because it provides a pathway to form C-C bond easily.

Cannizzaro reaction is an organic redox reaction in which disproportionation of aldehydes give carboxylic acids and alcohols. The reaction requires a strong base as the catalyst. In this redox reaction, a hydride transfers from one substrate to another.