What is the difference between a tetrad and a chromatid pair




















So each bivalent appears as 'tetrad' i. Homologous chromosomes exchange parts in a process called crossing as the first prophase stage of meiosis continues.

For this, homologous pairing and appearance of bivalent is important. Crossing over can take place when bivalent is in tetrad stage. What is the difference between a homologous chromosome and a tetrad?

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I provide resource materials and practice books matching to the curriculum and student level to gradually upgrade the performance of the learner. I have a two postgraduate qualifications in Orthopaedic Engineering and in Materials Enginnering. Any paternally inherited chromosome may also face either pole. The orientation of each tetrad is independent of the orientation of the other 22 tetrads. This event—the random or independent assortment of homologous chromosomes at the metaphase plate—is the second mechanism that introduces variation into the gametes or spores.

In each cell that undergoes meiosis, the arrangement of the tetrads is different. The number of variations is dependent on the number of chromosomes making up a set. There are two possibilities for orientation at the metaphase plate; the possible number of alignments therefore equals 2 n , where n is the number of chromosomes per set.

Humans have 23 chromosome pairs, which results in over eight million 2 23 possible genetically-distinct gametes. This number does not include the variability that was previously created in the sister chromatids by crossover. Given these two mechanisms, it is highly unlikely that any two haploid cells resulting from meiosis will have the same genetic composition Figure 3. Figure 3. In this case, there are two possible arrangements at the equatorial plane in metaphase I. The total possible number of different gametes is 2 n , where n equals the number of chromosomes in a set.

In this example, there are four possible genetic combinations for the gametes. To summarize the genetic consequences of meiosis I, the maternal and paternal genes are recombined by crossover events that occur between each homologous pair during prophase I.

In addition, the random assortment of tetrads on the metaphase plate produces a unique combination of maternal and paternal chromosomes that will make their way into the gametes. In anaphase I, the microtubules pull the linked chromosomes apart. The sister chromatids remain tightly bound together at the centromere. The chiasmata are broken in anaphase I as the microtubules attached to the fused kinetochores pull the homologous chromosomes apart Figure 4.

Figure 4. The process of chromosome alignment differs between meiosis I and meiosis II. In prometaphase I, microtubules attach to the fused kinetochores of homologous chromosomes, and the homologous chromosomes are arranged at the midpoint of the cell in metaphase I.

In anaphase I, the homologous chromosomes are separated. In prometaphase II, microtubules attach to the kinetochores of sister chromatids, and the sister chromatids are arranged at the midpoint of the cells in metaphase II. In anaphase II, the sister chromatids are separated.

In telophase, the separated chromosomes arrive at opposite poles. The remainder of the typical telophase events may or may not occur, depending on the species. In some organisms, the chromosomes decondense and nuclear envelopes form around the chromatids in telophase I.

The process is split into meiosis I and meiosis II, and both meiotic divisions have multiple phases. Meiosis I is a type of cell division unique to germ cells, while meiosis II is similar to mitosis. Meiosis I, the first meiotic division, begins with prophase I. During prophase I, the complex of DNA and protein known as chromatin condenses to form chromosomes. The pairs of replicated chromosomes are known as sister chromatids, and they remain joined at a central point called the centromere.

A large structure called the meiotic spindle also forms from long proteins called microtubules on each side, or pole, of the cell. Between prophase I and metaphase I, the pairs of homologous chromosome form tetrads. Within the tetrad, any pair of chromatid arms can overlap and fuse in a process called crossing-over or recombination.

Recombination is a process that breaks, recombines and rejoins sections of DNA to produce new combinations of genes. In metaphase I, the homologous pairs of chromosomes align on either side of the equatorial plate.



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